⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17605968 | 0.97 | — | — | |
| SCHEMBL12051177 | 0.88 | — | — | |
| SCHEMBL141637 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL11673221 | 0.85 | TSHR (0.33) | — | |
| Hydrochloric Acid SCHEMBL972691 | 0.85 | — | — | |
| SCHEMBL18413753 | 0.85 | TSHR (0.39) | — | |
| Hydrochloric Acid SCHEMBL1851281 | 0.83 | TSHR (0.37) | — | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL2375807 | 0.78 | — | — | |
| SCHEMBL27769742 | 0.72 | NSD2 (0.43) | — | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL21462059 | 0.69 | NSD2 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452985-A1 | CYCLOPENTATHIOPHENE CARBOXAMIDE DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-10-30 | — | — | EP | disclosed |
| CN-118414340-A | Cyclopentathiofuran carboxamide derivatives as platelet-activating factor receptor antagonists | 勃林格殷格翰国际有限公司 | 2024-07-30 | — | — | CN | disclosed |
| US-11992494-B2 | Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| WO-2023117914-A1 | CYCLOPENTATHIOPHENE CARBOXAMIDE DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-29 | — | — | WO | disclosed |
| US-20230190763-A1 | Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-22 | — | — | US | disclosed |
| EP-2492261-B1 | Analogs of benzoquinone-containing ansamycins for the treatment of cancer | INFINITY DISCOVERY INC (US) | 2015-02-18 | — | — | EP | disclosed |
| US-20130203724-A1 | Analogs of Benzoquinone-Containing Ansamycins and Methods of Use Thereof | INFINITY DISCOVERY, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130203724-A1 | Analogs of Benzoquinone-Containing Ansamycins and Methods of Use Thereof | INFINITY DISCOVERY, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| EP-1716119-B1 | Analogs of benzoquinone-containing ansamycins for the treatment of cancer | INFINITY DISCOVERY INC (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2492261-A1 | Analogs of benzoquinone-containing ansamycins for the treatment of cancer | Infinity Discovery, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |
| US-20090069280-A1 | ANALOGS OF BENZOQUINONE-CONTAINING ANSAMYCINS AND METHODS OF USE THEREOF | ADAMS JULIAN | 2009-03-12 | — | — | US | disclosed |
| US-20090069280-A1 | ANALOGS OF BENZOQUINONE-CONTAINING ANSAMYCINS AND METHODS OF USE THEREOF | ADAMS JULIAN | 2009-03-12 | — | — | US | disclosed |
| US-20090062250-A1 | Analogs of Benzoquinone-Containing Ansamycins and Methods of Use Thereof | INFINITY PHARMACEUTICALS, INC. | 2009-03-05 | — | — | US | disclosed |
| US-7375217-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375217-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7361647-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2008-04-22 | — | — | US | disclosed |
| US-7282493-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2007-10-16 | — | — | US | disclosed |
| US-7282493-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2007-10-16 | — | — | US | disclosed |
| US-4570014-A | Cycloalkanecarboxylic acid compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1986-02-11 | — | — | US | disclosed |
| US-4554017-A | Method and compositions for regulating plant growth using cycloalkane-carboxylic acid compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-19 | — | — | US | disclosed |