Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642077 | 0.88 | PARP10 (0.49) | EPHX2MAP4K4ACACBPARP10 | |
| SCHEMBL26351289 | 0.83 | EPHX2 (0.42) | CYP19A1MAPTEPHX2MAP4K4CYP2C9 | |
| SCHEMBL20400026 | 0.82 | HRH1 (0.43) | MAPTEPHX2MAP4K4CYP2C9CYP2J2 | |
| SCHEMBL31540092 | 0.82 | HRH1 (0.43) | MAPTEPHX2MAP4K4CYP2C9CYP2J2 | |
| SCHEMBL21525587 | 0.78 | ACSL1 (0.49) | EPHX2MAP4K4CYP2C9CYP2J2 | |
| SCHEMBL21997067 | 0.78 | EPHX2 (0.43) | CYP19A1MAPTEPHX2MAP4K4CYP2C9 | |
| SCHEMBL22849321 | 0.78 | EPHX2 (0.43) | CYP19A1MAPTEPHX2MAP4K4CYP2C9 | |
| SCHEMBL14654942 | 0.77 | CYP19A1 (0.49) | CYP19A1EPHX2GRIN1GRIN2B | |
| SCHEMBL29324903 | 0.77 | EPHX2 (0.41) | CYP19A1MAPTEPHX2MAP4K4CYP2C9 | |
| SCHEMBL14634351 | 0.77 | EPHX2 (0.41) | CYP19A1MAPTEPHX2MAP4K4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012164071-A1 | IMIDAZOLE DERIVATIVES | INTERVET INTERNATIONAL B.V. (NL) | 2012-12-06 | — | — | WO | disclosed |