SCHEMBL14130481 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	3/20	0.56

▸	THRB	P10828	1/20	0.44

▸	POLB	P06746	1/20	0.43

▸	APEX1	P27695	1/20	0.43

▸	HTT	P42858	1/20	0.43

▸	TDP1	Q9NUW8	1/20	0.43

▸	ALDH1A1	P00352	3/20	0.39

▸	CA1	P00915	1/20	0.30

▸	CA2	P00918	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3622054	0.98	TSHR (0.58)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL15355902	0.97	TSHR (0.61)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL15355891	0.97	TSHR (0.56)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL15355910	0.97	TSHR (0.56)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL15355889	0.97	TSHR (0.56)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL64810	0.96	TSHR (0.55)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL26561519	0.95	TSHR (0.53)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL15355907	0.93	TSHR (0.53)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL14032593	0.92	TSHR (0.65)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL17059112	0.92	TSHR (0.50)	TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7393520-B2	Decorative cosmetic and dermatological products	CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE)	2008-07-01	—	—	US	disclosed