SCHEMBL14132314

SCHEMBL14132314

CC(=N)N1CCC(Oc2ccc(C[C@H](NS(=O)(=O)c3ccccc3)C(=O)Oc3cccc(C(=N)N)c3)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 14/20 0.54
▸ PLG P00747 5/20 0.51
▸ ST14 Q9Y5Y6 5/20 0.51
▸ PLAU P00749 5/20 0.51
▸ F2 P00734 3/20 0.51
▸ HPN P05981 2/20 0.51
▸ HGFAC Q04756 1/20 0.51
▸ PLAT P00750 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14132093 0.86 F10 (0.56) F10PLGST14PLAUF2
Trifluoroacetic Acid SCHEMBL3898518 0.85 F2 (0.53) F10PLGST14PLAUF2
Trifluoroacetic Acid SCHEMBL3896012 0.83 F10 (0.56) F10PLGST14PLAUF2
SCHEMBL3897206 0.83 F10 (0.52) F10PLGST14PLAUF2
SCHEMBL14132072 0.82 F10 (0.57) F10PLGST14PLAUF2
SCHEMBL14132316 0.81 F10 (0.58) F10F2
SCHEMBL14132320 0.81 F10 (0.52) F10PLGST14PLAUF2
Trifluoroacetic Acid SCHEMBL5096319 0.81 F10 (0.49) F10PLGST14PLAUF2
SCHEMBL3909321 0.80 ST14 (0.62) F10PLGST14PLAUF2
SCHEMBL14132241 0.80 F10 (0.57) F10PLAUF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396844-B1 Benzamidine derivatives AJINOMOTO CO., INC. (JP) 2008-07-08 — — US disclosed
US-7396844-B1 Benzamidine derivatives AJINOMOTO CO., INC. (JP) 2008-07-08 — — US disclosed
Send feedback