Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610777 | 0.95 | KDM4E (0.34) | KDM4ETSHRRECQL | |
| SCHEMBL19424161 | 0.94 | CYP1A2 (0.31) | KDM4E | |
| SCHEMBL14669269 | 0.93 | KDM4E (0.33) | KDM4ETSHRRECQL | |
| Edetol SCHEMBL1005431 | 0.90 | KDM4E (0.34) | KDM4ETSHRRECQL | |
| SCHEMBL10537504 | 0.90 | KDM4E (0.34) | KDM4ETSHRRECQL | |
| SCHEMBL9785645 | 0.87 | KDM4E (0.38) | KDM4ETSHRRECQL | |
| Edetol SCHEMBL17728141 | 0.87 | KDM4E (0.38) | KDM4ETSHRRECQL | |
| SCHEMBL14980622 | 0.87 | KDM4E (0.32) | KDM4E | |
| SCHEMBL14980620 | 0.87 | KDM4E (0.32) | KDM4E | |
| SCHEMBL18427210 | 0.85 | CHRM2 (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250249-B1 | DELIVERY OF HYDROPHOBIC ACTIVE AGENT PARTICLES | SURMODICS INC (US) | 2021-12-08 | — | — | EP | disclosed |
| US-20210093753-A1 | ACTIVE AGENT DEPOTS FORMED IN SITU | BANK OF MONTREAL, AS COLLATERAL AGENT | 2021-04-01 | — | — | US | disclosed |
| WO-2018112196-A1 | HYDROPHOBIC ACTIVE AGENT PARTICLE COATINGS AND METHODS FOR TREATMENT | SURMODICS, INC. (US) | 2018-06-21 | — | — | WO | disclosed |
| WO-2017172922-A1 | LOCALIZED TREATMENT OF TISSUES THROUGH TRANSCATHETER DELIVERY OF ACTIVE AGENTS | SURMODICS, INC. (US) | 2017-10-05 | — | — | WO | disclosed |
| WO-2017173121-A1 | DRUG-CONTAINING PARTICULATE COMPOSITION WITH CATIONIC AGENT, ASSOCIATED MEDICAL DEVICES, AND METHODS FOR TREATMENT | SURMODICS, INC. (US) | 2017-10-05 | — | — | WO | disclosed |
| WO-2012162061-A1 | DELIVERY OF COATED HYDROPHOBIC ACTIVE AGENT PARTICLES | SURMODICS, INC. (US) | 2012-11-29 | — | — | WO | disclosed |