SCHEMBL14138239

SCHEMBL14138239

CNCc1ccc2cc(-n3ccc(OCc4ccc(C)cc4)cc3=O)ccc2n1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.52
KCNH2 Q12809 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4539828 0.91 MCHR1 (0.58) MCHR1KCNH2
SCHEMBL4532113 0.82 MCHR1 (0.61) MCHR1KCNH2
SCHEMBL4537952 0.82 MCHR1 (0.54) MCHR1KCNH2
SCHEMBL4533299 0.81 MCHR1 (0.58) MCHR1KCNH2
SCHEMBL4532639 0.81 MCHR1 (0.56) MCHR1KCNH2
SCHEMBL4532687 0.81 MCHR1 (0.59) MCHR1KCNH2
SCHEMBL4537503 0.80 MCHR1 (0.56) MCHR1KCNH2
SCHEMBL4535431 0.79 MCHR1 (0.58) MCHR1KCNH2
SCHEMBL4537942 0.79 MCHR1 (0.58) MCHR1KCNH2
SCHEMBL4535278 0.78 MCHR1 (0.62) MCHR1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1939194-A1 BICYCLIC AROMATIC SUBSTITUTED PYRIDONE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2008-07-02 EP disclosed