Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 19/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3591514 | 0.85 | BRAF (0.66) | BRAFPKM | |
| SCHEMBL14138862 | 0.85 | BRAF (0.63) | BRAFPKM | |
| SCHEMBL14138573 | 0.80 | BRAF (0.41) | BRAFPKM | |
| SCHEMBL3604502 | 0.79 | BRAF (0.71) | BRAFPKM | |
| SCHEMBL3601796 | 0.79 | BRAF (0.75) | BRAFPKM | |
| SCHEMBL14138556 | 0.79 | BRAF (0.73) | BRAFPKM | |
| SCHEMBL3601334 | 0.78 | BRAF (0.66) | BRAFPKM | |
| SCHEMBL14138512 | 0.77 | BRAF (0.58) | BRAFPKM | |
| SCHEMBL14138560 | 0.77 | BRAF (0.43) | BRAFPKM | |
| SCHEMBL14138509 | 0.75 | BRAF (0.47) | BRAFPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079277-A1 | CERTAIN PYRAZOLINE DERIVATIVES WITH KINASE INHIBITORY ACTIVITY | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |