Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.52 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832169 | 0.91 | F10 (0.62) | F10MAPTCCR1POLB | |
| SCHEMBL8445094 | 0.89 | F10 (0.45) | F10MAPTPKMTSHRMAPK1 | |
| SCHEMBL14039482 | 0.89 | F10 (0.47) | F10AVPR2POLB | |
| SCHEMBL3828731 | 0.81 | F10 (0.56) | F10POLB | |
| SCHEMBL3828596 | 0.80 | F10 (0.55) | F10CCR1POLBTSHR | |
| SCHEMBL3830301 | 0.76 | F10 (0.63) | F10RAB9AMAPTALDH1A1POLB | |
| SCHEMBL3835351 | 0.75 | F10 (0.58) | F10MAPTCCR1POLBTSHR | |
| SCHEMBL8467270 | 0.73 | SMN1; SMN2 (0.46) | F10RAB9APKMTSHRMAPK1 | |
| SCHEMBL8448048 | 0.73 | F10 (0.53) | F10POLB | |
| SCHEMBL4101126 | 0.73 | F10 (0.61) | F10RAB9AMAPTCCR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407972-B2 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | PFIZER INC. (US) | 2008-08-05 | — | — | US | disclosed |