Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322779 | 0.93 | KDR (0.72) | KDRFGFR3 | |
| Hydrochloric Acid SCHEMBL3322144 | 0.92 | KDR (0.71) | KDRFGFR3 | |
| SCHEMBL3322569 | 0.89 | KDR (0.72) | KDRFGFR3 | |
| SCHEMBL3320085 | 0.88 | KDR (0.71) | KDRFGFR3 | |
| SCHEMBL3321150 | 0.87 | KDR (0.80) | KDRFGFR3 | |
| SCHEMBL13336660 | 0.86 | KDR (0.73) | KDRFGFR3 | |
| SCHEMBL3319626 | 0.86 | FGFR3 (0.68) | KDRFGFR3 | |
| SCHEMBL13336643 | 0.86 | FGFR3 (0.80) | KDRFGFR3 | |
| SCHEMBL3325363 | 0.86 | KDR (0.79) | KDRFGFR3 | |
| SCHEMBL11925884 | 0.85 | KDR (1.00) | KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008078091-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS AS FGFR INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2008-07-03 | — | — | WO | disclosed |