Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14145945 | 0.85 | CCR4 (0.62) | CCR4 | |
| SCHEMBL1733009 | 0.85 | CCR4 (0.64) | CCR4 | |
| SCHEMBL1733194 | 0.85 | CCR4 (0.66) | CCR4 | |
| SCHEMBL1733210 | 0.85 | CCR4 (0.66) | CCR4 | |
| SCHEMBL1731930 | 0.84 | CCR4 (0.65) | CCR4 | |
| SCHEMBL4705556 | 0.84 | CCR4 (0.58) | CCR4 | |
| SCHEMBL4704359 | 0.83 | CCR4 (0.56) | CCR4 | |
| SCHEMBL3525377 | 0.82 | CCR4 (0.62) | CCR4 | |
| SCHEMBL14145961 | 0.82 | CCR4 (0.57) | CCR4 | |
| SCHEMBL4703788 | 0.82 | CCR4 (0.57) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633729-B1 | SULPHONAMIDE COMPOUNDS THAT MODULATE CHEMOKINE RECEPTOR ACTIVITY (CCR4) | ASTRAZENECA AB (SE) | 2008-07-30 | — | — | EP | disclosed |