Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.51 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14147966 | 0.88 | TRPV1 (0.48) | AKT1TRPV1DGAT2TP53ROCK2 | |
| SCHEMBL14148032 | 0.85 | TRPV1 (0.48) | TRPV1DGAT2 | |
| SCHEMBL14147719 | 0.80 | TRPV1 (0.49) | AKT1TRPV1DGAT2TP53ROCK2 | |
| SCHEMBL265347 | 0.80 | NAMPT (0.43) | TRPV1DGAT2ROCK2 | |
| SCHEMBL264842 | 0.80 | NAMPT (0.43) | TRPV1DGAT2ROCK2 | |
| SCHEMBL4787180 | 0.79 | FLT1 (0.48) | TRPV1DGAT2TP53PPARD | |
| SCHEMBL4021187 | 0.77 | TRPV1 (0.57) | TRPV1DGAT2 | |
| SCHEMBL14147888 | 0.77 | TRPV1 (0.49) | TRPV1DGAT2ROCK2 | |
| SCHEMBL4021335 | 0.76 | ROS1 (0.55) | TRPV1DGAT2 | |
| SCHEMBL13332063 | 0.76 | TRPV1 (0.57) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090434-A1 | SUBSTITUTED N-BICYCLICALKYL BICYCLIC CARBOXYAMIDE COMPOUNDS | PFIZER JAPAN INC. (JP) | 2008-07-31 | — | — | WO | disclosed |