Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 13/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 10/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985497 | 0.85 | EGLN3 (0.64) | EGLN3EGLN1EGLN2CYSLTR2HIF1A | |
| SCHEMBL4988805 | 0.73 | EGLN1 (0.61) | EGLN3EGLN1 | |
| SCHEMBL4997381 | 0.72 | EGLN3 (0.69) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL4988292 | 0.71 | EGLN1 (0.56) | EGLN3EGLN1 | |
| SCHEMBL4996212 | 0.71 | EGLN3 (0.64) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL4988787 | 0.71 | EGLN1 (0.55) | EGLN3EGLN1EGLN2 | |
| SCHEMBL14123916 | 0.70 | EGLN3 (0.58) | EGLN3EGLN1 | |
| SCHEMBL4992312 | 0.70 | EGLN3 (0.47) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL4992208 | 0.70 | EGLN3 (0.63) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL5000261 | 0.70 | EGLN3 (0.63) | EGLN3EGLN1EGLN2CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | disclosed |