Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 4/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18071792 | 0.88 | TTR (0.45) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL5861799 | 0.83 | ESR1 (0.56) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL18069261 | 0.83 | TTR (0.48) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL14148735 | 0.82 | EGFR (0.43) | EGFRCYP3A4ESR1MET | |
| SCHEMBL16303520 | 0.82 | CNKSR1 (0.48) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4718050 | 0.82 | MAPT (0.48) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4718052 | 0.82 | MAPT (0.48) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL29607942 | 0.82 | MAPT (0.48) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL24844752 | 0.81 | TTR (0.46) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL13311783 | 0.81 | CYP3A4 (0.47) | TTRDPP4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053479-A9 | SELF-IMMOLATIVE POLYMERS | UNIV RAMOT (IL) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008053479-A1 | SELF-IMMOLATIVE POLYMERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2008-05-08 | — | — | WO | disclosed |