Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.53 |
| ▸ | HTR2B | P41595 | 19/20 | 0.53 |
| ▸ | HTR2A | P28223 | 18/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13118842 | 0.87 | HTR2C (0.68) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL3557536 | 0.83 | HTR2C (0.61) | HTR2CHTR2BHTR2A | |
| SCHEMBL3563026 | 0.80 | HTR2C (0.68) | HTR2CHTR2BHTR2A | |
| SCHEMBL13118845 | 0.77 | HTR2C (0.63) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL3563763 | 0.73 | HTR2C (0.58) | HTR2CHTR2BHTR2A | |
| SCHEMBL11379514 | 0.72 | HTR2C (0.62) | HTR2CHTR2BHTR2A | |
| SCHEMBL11380467 | 0.72 | HTR2C (0.62) | HTR2CHTR2BHTR2A | |
| SCHEMBL13119029 | 0.70 | HTR2A (0.72) | HTR2CHTR2BHTR2A | |
| SCHEMBL13119027 | 0.70 | HTR2A (0.72) | HTR2CHTR2BHTR2A | |
| SCHEMBL13118882 | 0.70 | HTR2C (1.00) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675859-B1 | MODULATORS OF SEROTONIN RECEPTORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-05 | — | — | EP | disclosed |