Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3553395 | 0.91 | SCN5A (0.40) | SCN5AHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL3556086 | 0.83 | HTR2C (0.45) | SCN5AHTR2AHTR2CHTR2B | |
| SCHEMBL3553613 | 0.75 | HTR2C (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL13118805 | 0.74 | HTR2C (0.62) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3554417 | 0.73 | HTR2C (0.61) | HTR2AHTR2CHTR2B | |
| SCHEMBL13118808 | 0.66 | HTR2C (0.70) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3554505 | 0.66 | HTR2C (0.69) | HTR2AHTR2CHTR2B | |
| SCHEMBL3553621 | 0.65 | HTR2C (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL3559944 | 0.65 | HTR2A (0.58) | HTR2AHTR2CHTR2B | |
| SCHEMBL14110499 | 0.65 | HTR2C (0.45) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675859-B1 | MODULATORS OF SEROTONIN RECEPTORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-05 | — | — | EP | disclosed |