Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207239 | 0.81 | — | — | |
| SCHEMBL258152 | 0.74 | SLC22A6 (0.50) | BHMTSLC22A6CACNA2D1CACNB3CACNA1C | |
| SCHEMBL11233846 | 0.73 | CACNA2D1 (0.38) | BHMTITGB3ITGA2BSLC22A6CACNA2D1 | |
| SCHEMBL1802415 | 0.73 | TDP1 (0.41) | BHMTITGB3ITGA2BSLC22A6CACNA2D1 | |
| SCHEMBL16755874 | 0.73 | FFAR1 (0.36) | BHMTITGB3ITGA2BSLC22A6CACNA2D1 | |
| SCHEMBL3849299 | 0.72 | TDP1 (0.33) | BHMTITGB3ITGA2BSLC22A6CACNA2D1 | |
| SCHEMBL14109598 | 0.72 | SLC22A6 (0.47) | BHMTSLC22A6CACNA2D1CACNB3CACNA1C | |
| SCHEMBL11112412 | 0.72 | SLC22A6 (0.47) | BHMTSLC22A6CACNA2D1CACNB3CACNA1C | |
| Ethane SCHEMBL5968227 | 0.72 | SLC22A6 (0.47) | BHMTSLC22A6CACNA2D1CACNB3CACNA1C | |
| SCHEMBL10902055 | 0.72 | SLC22A6 (0.47) | BHMTSLC22A6CACNA2D1CACNB3CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012163563-A1 | NEW STRONTIUM SALTS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF OSTEOPOROSIS | LACER, S.A. (ES) | 2012-12-06 | — | — | WO | disclosed |
| EP-2530068-A1 | New strontium salts, synthesis and use thereof in the treatment of osteoporosis | LACER, S.A. (ES) | 2012-12-05 | — | — | EP | disclosed |