Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.78 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.78 |
| ▸ | ITGB7 | P26010 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413087 | 0.95 | ITGB1 (0.86) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413100 | 0.94 | ITGB1 (0.87) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413074 | 0.89 | ITGB1 (0.87) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413048 | 0.88 | ITGB1 (0.98) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413068 | 0.88 | ITGB1 (1.00) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413073 | 0.86 | ITGB1 (0.84) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2608690 | 0.85 | ITGB1 (0.86) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413011 | 0.85 | ITGB1 (0.82) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413108 | 0.84 | ITGB1 (1.00) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413159 | 0.84 | ITGB1 (0.90) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940827-B1 | CARBAMATE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2011-03-16 | — | — | EP | disclosed |