SCHEMBL1415224

SCHEMBL1415224

N#COC(=O)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5489369 0.79
SCHEMBL15901567 0.75
SCHEMBL6478357 0.73
SCHEMBL2778853 0.72
SCHEMBL2778855 0.69
SCHEMBL28718957 0.69
SCHEMBL29250074 0.69
SCHEMBL31489164 0.69
SCHEMBL27264279 0.69
SCHEMBL13558469 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114360-B1 HAIR CARE COMPOSITION PROCTER & GAMBLE (US) 2015-03-25 EP claimed
US-20140356305-A1 Hair Care Composition PROCTER & GAMBLE (US) 2014-12-04 US claimed
US-7981167-B2 Method and composition for maintaining hair dye color THE PROCTER & GAMBLE COMPANY (US) 2011-07-19 US claimed
WO-2010014763-A2 METHOD AND COMPOSITION FOR MAINTAINING HAIR DYE COLOR THE PROCTER & GAMBLE COMPANY (US) 2010-02-04 WO claimed
US-20100028286-A1 Method and Composition for Stabilizing Hair Moisture Levels THE PROCTER & GAMBLE COMPANY 2010-02-04 US claimed
US-20100028279-A1 Method and Composition for Maintaining Hair Dye Color THE PROCTER & GAMBLE COMPANY 2010-02-04 US claimed
EP-2114360-A1 HAIR CARE COMPOSITION The Procter & Gamble Company (US) 2009-11-11 EP claimed
WO-2009088520-A1 HAIR CARE COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2009-07-16 WO claimed
US-20090022681-A1 Hair Care Composition THE PROCTER & GAMBLE COMPANY 2009-01-22 US claimed
US-20080210253-A1 Hair care composition PROCTER & GAMBLE COMPANY, THE 2008-09-04 US claimed
US-20080187506-A1 Hair care composition PROCTER & GAMBLE COMPANY, THE 2008-08-07 US claimed
CN-114591727-B Organic long-afterglow luminescent material, preparation and application 中国科学院上海有机化学研究所 2024-06-28 CN disclosed
CN-117321070-A Virus targeting to hematopoietic stem cells 麻省理工学院 2023-12-29 CN disclosed
CN-106999444-B Enhanced loading of small molecule compounds with intact bacterially derived vesicles 安吉尼科分子传输公司 2023-12-12 CN disclosed
CN-108486088-B Nitrilase mutant and application thereof 浙江工业大学 2021-02-02 CN disclosed
US-20080210253-A1 Hair care composition PROCTER & GAMBLE COMPANY, THE 2008-09-04 US disclosed
US-20080187506-A1 Hair care composition PROCTER & GAMBLE COMPANY, THE 2008-08-07 US disclosed
EP-0436183-B1 Process for the preparation of symmetrical azodinitrile dicarboxylic acids from keto acids GOODRICH CO B F (US) 1995-03-15 EP disclosed
US-5037963-A Reacting a keto acid with a metal cyanide and an ammonia source, removing ammonia source, desolventizing, reacting with a metal hydrochlorite, and neutralization THE B. F. GOODRICH COMPANY (US) 1991-08-06 US disclosed
EP-0436183-A1 Process for the preparation of symmetrical azodinitrile dicarboxylic acids from keto acids THE B.F. GOODRICH COMPANY (US) 1991-07-10 EP disclosed