Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 1.00 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13570581 | 1.00 | HRH3 (1.00) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL14158615 | 1.00 | HRH3 (1.00) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL30938557 | 1.00 | HRH3 (1.00) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL14152810 | 1.00 | HRH3 (1.00) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL3348406 | 1.00 | HRH3 (1.00) | HRH3PARP10PARP15PARP2MAOB | |
| Hydrochloric Acid SCHEMBL13585720 | 0.99 | HRH3 (0.97) | HRH3PARP10PARP15PARP2MAOB | |
| Hydrochloric Acid SCHEMBL13585722 | 0.99 | HRH3 (0.97) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL4489280 | 0.97 | HRH3 (0.95) | HRH3PARP10PARP15PARP2MAOB | |
| Oxalic Acid SCHEMBL4494998 | 0.96 | HRH3 (0.93) | HRH3PARP10PARP15PARP2MAOB | |
| Oxalic Acid SCHEMBL14150312 | 0.96 | HRH3 (0.93) | HRH3PARP10PARP15PARP2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012168664-A1 | 4-{3-[TRANS-HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL]PROPOXY}BENZAMIDE, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN SAME | LES LABORATOIRES SERVIER (FR) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012168664-A1 | 4-{3-[TRANS-HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL]PROPOXY}BENZAMIDE, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN SAME | LES LABORATOIRES SERVIER (FR) | 2012-12-13 | — | — | WO | disclosed |