Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103778 | 0.87 | HTT (0.44) | OPRM1TRPV1 | |
| SCHEMBL3594760 | 0.87 | HTT (0.44) | OPRM1TRPV1 | |
| SCHEMBL146513 | 0.82 | HTT (0.43) | — | |
| SCHEMBL146514 | 0.82 | HTT (0.43) | — | |
| SCHEMBL106474 | 0.79 | HTT (0.43) | — | |
| SCHEMBL106476 | 0.79 | HTT (0.43) | — | |
| SCHEMBL106475 | 0.79 | HTT (0.43) | — | |
| SCHEMBL3599015 | 0.77 | HTT (0.40) | — | |
| SCHEMBL106171 | 0.77 | HTT (0.40) | — | |
| SCHEMBL13072519 | 0.77 | HTT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-B1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | KOWA CO (JP) | 2013-11-06 | — | — | EP | disclosed |
| EP-2426113-A1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | Kowa Company, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |