Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103111 | 0.93 | KDM1A (0.50) | ALOX5KDM1ARAB9ANPC1PKM | |
| SCHEMBL103112 | 0.93 | KDM1A (0.50) | ALOX5KDM1ARAB9ANPC1PKM | |
| SCHEMBL283942 | 0.93 | KDM1A (0.50) | ALOX5KDM1ARAB9ANPC1PKM | |
| SCHEMBL10092621 | 0.89 | KDM1A (0.54) | ALOX5KDM1ARAB9ANPC1GAA | |
| SCHEMBL15913193 | 0.82 | FLT3 (0.43) | ALOX5KDM1ARAB9ANPC1PKM | |
| SCHEMBL14060096 | 0.82 | FLT3 (0.43) | ALOX5KDM1ARAB9ANPC1PKM | |
| SCHEMBL14153055 | 0.81 | TAAR1 (0.55) | ALOX5KDM1ARAB9APKMGAA | |
| SCHEMBL21215222 | 0.81 | KDM1A (0.60) | KDM1ARAB9ANPC1GAALMNA | |
| SCHEMBL1009423 | 0.80 | GRIN2B (0.58) | BCL2L1KDM1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1009422 | 0.80 | GRIN2B (0.58) | BCL2L1KDM1ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012162635-A1 | METABOTROPIC GLUTAMATE RECEPTORS 5 MODULATORS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2012-11-29 | — | — | WO | disclosed |