SCHEMBL1415327

SCHEMBL1415327

CN1CCN(CC(=O)Nc2cc3[nH]c(-n4cc(C(=O)O)cn4)nc3cc2Cl)CC1

nearest known ligand 0.93

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 20/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1192760 0.96 EGLN1 (1.00) EGLN1
SCHEMBL1192640 0.88 EGLN1 (1.00) EGLN1
SCHEMBL1193461 0.86 EGLN1 (1.00) EGLN1
SCHEMBL15936184 0.84 EGLN1 (0.77) EGLN1
SCHEMBL1193071 0.82 EGLN1 (1.00) EGLN1
SCHEMBL1192837 0.79 EGLN1 (1.00) EGLN1
SCHEMBL12875964 0.78 EGLN1 (0.82) EGLN1
SCHEMBL1192802 0.77 EGLN1 (1.00) EGLN1
SCHEMBL1193134 0.77 EGLN1 (1.00) EGLN1
SCHEMBL1415258 0.76 EGLN1 (0.92) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294066-A1 BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS Janssen Pharmaceutica, N.V. (BE) 2011-03-16 EP disclosed