Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193190 | 0.96 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL1193496 | 0.86 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL1192802 | 0.86 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL12876162 | 0.86 | EGLN1 (0.78) | EGLN1 | |
| SCHEMBL1192446 | 0.85 | EGLN1 (0.92) | EGLN1 | |
| SCHEMBL1193299 | 0.85 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL1192914 | 0.85 | EGLN1 (0.92) | EGLN1 | |
| SCHEMBL1192823 | 0.85 | EGLN1 (0.93) | EGLN1 | |
| SCHEMBL1192978 | 0.84 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL12875906 | 0.84 | EGLN1 (0.82) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294066-A1 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009134750-A1 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | WO | disclosed |