Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415659 | 0.88 | POLB (0.50) | SMN1; SMN2CCR6CCR5LMNAMAPT | |
| SCHEMBL1415600 | 0.87 | KDM4E (0.49) | KCNQ1SMN1; SMN2CCR6CCR5LMNA | |
| SCHEMBL1415639 | 0.87 | KDM4E (0.49) | KCNQ1SMN1; SMN2CCR6CCR5LMNA | |
| SCHEMBL1415645 | 0.87 | KDM4E (0.49) | KCNQ1SMN1; SMN2CCR6CCR5LMNA | |
| SCHEMBL1415476 | 0.87 | KDM4E (0.49) | KCNQ1SMN1; SMN2CCR6CCR5LMNA | |
| SCHEMBL1415793 | 0.79 | KDM4E (0.45) | SMN1; SMN2CCR6CCR5LMNAKDM4E | |
| SCHEMBL13198804 | 0.78 | MAPT (0.42) | KCNQ1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL1415875 | 0.77 | TYR (0.43) | SMN1; SMN2LMNAMAPTHTTKDM4E | |
| SCHEMBL4501356 | 0.76 | POLB (0.49) | KCNQ1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL4501351 | 0.76 | POLB (0.49) | KCNQ1SMN1; SMN2LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807421-B1 | 2-AMIDO-4-PHENYLTHIAZOLE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2011-03-16 | — | — | EP | claimed |