Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.82 |
| ▸ | CNR1 | P21554 | 8/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.78 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | MLNR | O43193 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14155495 | 0.97 | CNR2 (0.85) | CNR2CNR1CYP2C9GPR55CYP1A2 | |
| SCHEMBL14155483 | 0.93 | CNR1 (0.81) | CNR2CNR1CYP2C9GPR55CYP1A2 | |
| SCHEMBL14155471 | 0.92 | CNR1 (0.83) | CNR2CNR1CYP2C9GPR55CYP1A2 | |
| SCHEMBL14155457 | 0.91 | CNR1 (0.83) | CNR2CNR1CYP2C9GPR55CYP1A2 | |
| SCHEMBL14155455 | 0.91 | CNR1 (0.82) | CNR2CNR1CYP2C9GPR55CYP1A2 | |
| SCHEMBL14155469 | 0.90 | CNR1 (0.84) | CNR2CNR1CYP2C9GPR55CYP1A2 | |
| SCHEMBL3815250 | 0.88 | CNR2 (0.91) | CNR2CNR1CYP2C9GPR55CYP1A2 | |
| SCHEMBL29835959 | 0.88 | CNR1 (1.00) | CNR2CNR1CYP2C9GPR55CYP1A2 | |
| SCHEMBL1517458 | 0.88 | CNR1 (1.00) | CNR2CNR1CYP2C9GPR55CYP1A2 | |
| SCHEMBL14155484 | 0.87 | CNR1 (0.71) | CNR2CNR1CYP2C9GPR55CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075118-A1 | NOVEL CB1 ANTAGONISTS AND THEIR PREPARATION | RICHTER GEDEON NYRT. (HU) | 2008-06-26 | — | — | WO | disclosed |