Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | HBB | P68871 | 1/20 | 0.65 |
| ▸ | PNP | P00491 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346544 | 0.91 | PNP (0.65) | CYP1A2HBBPNPLMNATP53 | |
| SCHEMBL9346554 | 0.91 | PNP (0.65) | CYP1A2HBBPNPLMNATP53 | |
| SCHEMBL5982123 | 0.88 | HIF1A (0.59) | CYP1A2HBBPNPLMNATP53 | |
| SCHEMBL5982127 | 0.88 | HIF1A (0.59) | CYP1A2HBBPNPLMNATP53 | |
| SCHEMBL21795436 | 0.88 | CYP1A2 (0.64) | CYP1A2HBBPNPLMNATP53 | |
| SCHEMBL21795432 | 0.88 | CYP1A2 (0.64) | CYP1A2HBBPNPLMNATP53 | |
| SCHEMBL21795433 | 0.88 | CYP1A2 (0.64) | CYP1A2HBBPNPLMNATP53 | |
| SCHEMBL21795365 | 0.87 | CYP1A2 (0.61) | CYP1A2HBBPNPLMNATP53 | |
| SCHEMBL21795366 | 0.87 | CYP1A2 (0.61) | CYP1A2HBBPNPLMNATP53 | |
| SCHEMBL23982120 | 0.85 | PNP (0.79) | CYP1A2HBBPNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |