Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051260 | 0.87 | CSNK2B (0.38) | CSNK2BKDM4EGAAMAPT | |
| SCHEMBL2051265 | 0.87 | CSNK2B (0.38) | CSNK2BKDM4EGAAMAPT | |
| SCHEMBL2028226 | 0.78 | CSNK2B (0.46) | CSNK2BALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL1935775 | 0.78 | CSNK2B (0.46) | CSNK2BALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL2028224 | 0.78 | CSNK2B (0.46) | CSNK2BALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL12586941 | 0.75 | CSNK2B (0.45) | CSNK2BALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL2032996 | 0.73 | CSNK2B (0.32) | CSNK2BKDM4EGAAMAPT | |
| SCHEMBL2032992 | 0.73 | CSNK2B (0.32) | CSNK2BKDM4EGAAMAPT | |
| SCHEMBL15368816 | 0.73 | CSNK2B (0.36) | CSNK2B | |
| SCHEMBL1486088 | 0.73 | CSNK2B (0.41) | CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |