Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415645 | 0.86 | KDM4E (0.49) | ALDH1A1KDM4ETYRPOLBLMNA | |
| SCHEMBL1415476 | 0.86 | KDM4E (0.49) | ALDH1A1KDM4ETYRPOLBLMNA | |
| SCHEMBL1415600 | 0.86 | KDM4E (0.49) | ALDH1A1KDM4ETYRPOLBLMNA | |
| SCHEMBL1415639 | 0.86 | KDM4E (0.49) | ALDH1A1KDM4ETYRPOLBLMNA | |
| SCHEMBL1415875 | 0.85 | TYR (0.43) | ALDH1A1KDM4ETYRPOLBLMNA | |
| SCHEMBL1415531 | 0.85 | TYR (0.42) | ALDH1A1KDM4ETYRPOLBLMNA | |
| SCHEMBL1415372 | 0.84 | TYR (0.43) | ALDH1A1KDM4ETYRPOLBLMNA | |
| SCHEMBL1415297 | 0.83 | TYR (0.42) | ALDH1A1KDM4ETYRPOLBLMNA | |
| SCHEMBL1415256 | 0.83 | TYR (0.42) | ALDH1A1KDM4ETYRPOLBLMNA | |
| SCHEMBL1415907 | 0.83 | TYR (0.42) | ALDH1A1KDM4ETYRPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807421-B1 | 2-AMIDO-4-PHENYLTHIAZOLE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2011-03-16 | — | — | EP | claimed |