⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18900634 | 1.00 | — | — | |
| SCHEMBL2743237 | 1.00 | — | — | |
| SCHEMBL14159200 | 1.00 | — | — | |
| SCHEMBL13349218 | 1.00 | — | — | |
| SCHEMBL23188550 | 1.00 | — | — | |
| SCHEMBL18900552 | 1.00 | — | — | |
| SCHEMBL23188630 | 1.00 | — | — | |
| SCHEMBL18900658 | 1.00 | — | — | |
| SCHEMBL178436 | 0.97 | — | — | |
| SCHEMBL20992349 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11207211-B2 | Lacrimal drug delivery device | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2021-12-28 | — | — | US | disclosed |
| EP-3330256-B1 | HETEROCYCLIC DERIVATIVE HAVING TrkA-INHIBITING ACTIVITY | SHIONOGI & CO (JP) | 2021-06-16 | — | — | EP | disclosed |
| WO-2018117127-A1 | AGENT FOR REMOVING UNDIFFERENTIATED IPS CELLS | 大日本住友製薬株式会社 | 2018-06-28 | — | — | WO | disclosed |
| EP-3330256-A1 | HETEROCYCLIC DERIVATIVE HAVING TrkA-INHIBITING ACTIVITY | Shionogi & Co., Ltd. (JP) | 2018-06-06 | — | — | EP | disclosed |
| US-9679988-B2 | Polysilicon design for replacement gate technology | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2017-06-13 | — | — | US | disclosed |
| EP-1930021-A2 | Novel amide derivatives as growth hormone secretagogues | Kaken Pharmaceutical Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |