SCHEMBL1416043

SCHEMBL1416043

[CH2]CNC(=O)NCc1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
EPHX2 P34913 1/20 0.61
TP53 P04637 1/20 0.58
LMNA P02545 1/20 0.57
PTPN1 P18031 1/20 0.57
PPID Q08752 1/20 0.54
P2RX7 Q99572 1/20 0.54
GAA P10253 1/20 0.53
CFD P00746 1/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
TSHR P16473 1/20 0.52
CYP2C19 P33261 1/20 0.52
HPGD P15428 1/20 0.51
KDM4E B2RXH2 1/20 0.51
GSK3B P49841 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714625 0.89 EPHX1 (0.77) EPHX1SMN1; SMN2EPHX2TP53LMNA
SCHEMBL5612314 0.82 EPHX2 (0.73) EPHX1SMN1; SMN2EPHX2TP53LMNA
SCHEMBL4588571 0.82 EPHX1 (0.61) EPHX1SMN1; SMN2EPHX2TP53LMNA
SCHEMBL6033584 0.81 TP53 (0.75) EPHX1SMN1; SMN2EPHX2TP53LMNA
SCHEMBL6025573 0.81 MEN1 (0.81) EPHX1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL970225 0.80 SMN1; SMN2 (0.70) EPHX1SMN1; SMN2EPHX2TP53LMNA
SCHEMBL6435482 0.80 EPHX2 (0.83) EPHX1SMN1; SMN2EPHX2TP53LMNA
SCHEMBL7393991 0.80 EPHX1 (0.65) EPHX1SMN1; SMN2EPHX2TP53LMNA
SCHEMBL26406641 0.80 EPHX1 (0.65) EPHX1SMN1; SMN2EPHX2TP53LMNA
SCHEMBL13773684 0.79 EPHX1 (0.59) EPHX1SMN1; SMN2EPHX2TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2165830-A1 Lithographic printing plate precursor and printing method using the same Fujifilm Corporation (JP) 2010-03-24 EP disclosed