SCHEMBL14162017

SCHEMBL14162017

C=C(c1ccc(C)c(NC(N)=O)c1)N1CCC(c2ccc(C#N)cc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14162205 0.91 FASN (0.63) FASN
SCHEMBL4205023 0.90 FASN (0.67) FASN
SCHEMBL14210024 0.89 FASN (0.55) FASN
SCHEMBL14162027 0.89 FASN (0.58) FASN
SCHEMBL14162033 0.88 FASN (0.52) FASN
SCHEMBL14162012 0.88 FASN (0.60) FASN
SCHEMBL14162044 0.88 FASN (0.53) FASN
SCHEMBL14162034 0.87 FASN (0.53) FASN
SCHEMBL14209246 0.86 FASN (0.51) FASN
SCHEMBL14161573 0.86 FASN (0.52) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed