SCHEMBL1417023

SCHEMBL1417023

CCC(CC)COc1cc(C#Cc2ccccc2)cc(Sc2ccc(OCC(=O)O)c(C)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.54
PPARA Q07869 3/20 0.52
PPARG P37231 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1810879 0.92 PPARD (0.46) PPARDPPARA
SCHEMBL5051544 0.87 PPARD (0.43) PPARDPPARAPPARG
SCHEMBL10328033 0.86 PPARD (0.55) PPARDPPARAPPARG
SCHEMBL1417385 0.83 PPARD (0.58) PPARDPPARAPPARG
SCHEMBL1814043 0.82 PPARD (0.51) PPARDPPARAPPARG
SCHEMBL1813527 0.81 PPARD (0.52) PPARDPPARAPPARG
SCHEMBL1417937 0.80 PTGDR2 (0.48) PPARDPPARAPPARG
SCHEMBL1417053 0.80 PPARD (0.49) PPARDPPARAPPARG
SCHEMBL2068502 0.80 PPARD (0.53) PPARDPPARAPPARG
SCHEMBL1417273 0.78 PPARD (0.55) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1899302-B1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS HIGH POINT PHARMACEUTICALS LLC (US) 2011-10-19 EP claimed
US-7943669-B2 Phenoxy acetic acids as PPAR delta activators HIGH POINT PHARMACEUTICALS, LLC (US) 2011-05-17 US claimed
US-20090192162-A1 Phenoxy Acetic Acids as PPAR Delta Activators TRANSTECH PHARMA, INC. (NC) 2009-07-30 US claimed
EP-1899302-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS Novo Nordisk A/S (DK) 2008-03-19 EP claimed
WO-2007003581-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS NOVO NORDISK A/S (DK) 2007-01-11 WO claimed
US-8426473-B2 Phenoxy acetic acids as PPAR delta activators High Point Pharnaceuticals, LLC (US) 2013-04-23 US disclosed
US-8426473-B2 Phenoxy acetic acids as PPAR delta activators High Point Pharnaceuticals, LLC (US) 2013-04-23 US disclosed
US-8426473-B2 Phenoxy acetic acids as PPAR delta activators High Point Pharnaceuticals, LLC (US) 2013-04-23 US disclosed
US-20120232080-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS HIGH POINT PHARMACEUTICALS, LLC (US) 2012-09-13 US disclosed
US-20120232080-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS HIGH POINT PHARMACEUTICALS, LLC (US) 2012-09-13 US disclosed
US-8217086-B2 Phenoxy acetic acids as PPAR delta activators HIGH POINT PHARMACEUTICALS, LLC (US) 2012-07-10 US disclosed
US-8217086-B2 Phenoxy acetic acids as PPAR delta activators HIGH POINT PHARMACEUTICALS, LLC (US) 2012-07-10 US disclosed
US-20110183982-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS HIGH POINT PHARMACEUTICALS, LLC (US) 2011-07-28 US disclosed
US-7943669-B2 Phenoxy acetic acids as PPAR delta activators HIGH POINT PHARMACEUTICALS, LLC (US) 2011-05-17 US disclosed
US-7943669-B2 Phenoxy acetic acids as PPAR delta activators HIGH POINT PHARMACEUTICALS, LLC (US) 2011-05-17 US disclosed
EP-2298742-A1 Phenoxy acetic acids as PPAR delta activators High Point Pharmaceuticals, LLC (US) 2011-03-23 EP disclosed
US-20090192162-A1 Phenoxy Acetic Acids as PPAR Delta Activators TRANSTECH PHARMA, INC. (NC) 2009-07-30 US disclosed
US-20090192162-A1 Phenoxy Acetic Acids as PPAR Delta Activators TRANSTECH PHARMA, INC. (NC) 2009-07-30 US disclosed
EP-1899302-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS Novo Nordisk A/S (DK) 2008-03-19 EP disclosed
WO-2007003581-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS NOVO NORDISK A/S (DK) 2007-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090192162-A1 Phenoxy Acetic Acids as PPAR Delta Activators PPARA, PPARG, PPARD PPARD 3/4885PPARA 1/4885PPARG 2/4885
US-20120232080-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS PPARA, PPARG, PPARD PPARD 3/4885PPARA 1/4885PPARG 2/4885
US-20110183982-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS PPARA, PPARG, PPARD PPARD 3/4885PPARA 1/4885PPARG 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.