Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923598 | 1.00 | AAK1 (0.53) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL3375872 | 1.00 | AAK1 (0.53) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL19227630 | 0.88 | CA1 (0.58) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL3389057 | 0.88 | CA1 (0.49) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL89665 | 0.87 | CA1 (0.47) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL90371 | 0.87 | CA1 (0.47) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL90567 | 0.84 | AAK1 (0.51) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL16638817 | 0.83 | CTSK (0.45) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL15250454 | 0.83 | CA1 (0.53) | AAK1CA1CA2CA7CTSL | |
| SCHEMBL1987513 | 0.83 | CA1 (0.45) | AAK1CA1CA2CA7CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| EP-1857459-A2 | Pyrazolopyrimidine compound and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2007-11-21 | — | — | EP | disclosed |