Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 3/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14175362 | 0.85 | CDK1 (0.41) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175342 | 0.84 | CCNB2 (0.39) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175341 | 0.83 | CDK1 (0.40) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175364 | 0.82 | CDK1 (0.39) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175345 | 0.82 | CDK1 (0.39) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175374 | 0.82 | CCNB2 (0.40) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175382 | 0.81 | CDK1 (0.41) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175349 | 0.81 | CCNB2 (0.39) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175369 | 0.81 | CDK1 (0.40) | CCNB2CDK1CCNB1CCNB3HDAC1 | |
| SCHEMBL14175343 | 0.80 | CCNB2 (0.38) | CCNB2CDK1CCNB1CCNB3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388002-B2 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-06-17 | — | — | US | disclosed |