Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 5/20 | 0.42 |
| ▸ | CDK1 | P06493 | 5/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.42 |
| ▸ | CDK2 | P24941 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14175365 | 0.93 | CDK1 (0.43) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175362 | 0.91 | CDK1 (0.41) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175387 | 0.86 | CCNB2 (0.41) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175360 | 0.85 | CDK1 (0.48) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175342 | 0.83 | CCNB2 (0.39) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175363 | 0.83 | CDK1 (0.44) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175341 | 0.82 | CDK1 (0.40) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175364 | 0.82 | CDK1 (0.39) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175345 | 0.82 | CDK1 (0.39) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14175349 | 0.81 | CCNB2 (0.39) | CCNB2CDK1CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388002-B2 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-06-17 | — | — | US | disclosed |