Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 12/20 | 1.00 |
| ▸ | CDK1 | P06493 | 2/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 1.00 |
| ▸ | CDK6 | Q00534 | 2/20 | 1.00 |
| ▸ | GSK3B | P49841 | 1/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 1/20 | 1.00 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866238 | 1.00 | CDK4 (1.00) | CDK4CDK1CDK2CDK6GSK3B | |
| SCHEMBL13866185 | 0.90 | CDK4 (0.82) | CDK4CDK1CDK2CDK6GSK3B | |
| SCHEMBL13866248 | 0.90 | CDK4 (0.82) | CDK4CDK1CDK2CDK6GSK3B | |
| SCHEMBL13866152 | 0.90 | CDK4 (0.81) | CDK4CDK1CDK2CDK6GSK3B | |
| SCHEMBL13866180 | 0.90 | CDK4 (0.81) | CDK4CDK1CDK2CDK6GSK3B | |
| SCHEMBL13866190 | 0.89 | CDK4 (0.80) | CDK4CDK1CDK2CDK6GSK3B | |
| SCHEMBL13866171 | 0.89 | CDK4 (0.80) | CDK4CDK1CDK2CDK6GSK3B | |
| SCHEMBL13866203 | 0.88 | CDK4 (0.79) | CDK4CDK1CDK2CDK6GSK3B | |
| SCHEMBL13866169 | 0.88 | CDK4 (0.79) | CDK4CDK1CDK2CDK6GSK3B | |
| SCHEMBL13866200 | 0.88 | CDK4 (0.79) | CDK4CDK1CDK2CDK6GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4256086-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | Cedars-Sinai Medical Center (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-4162076-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | Cedars-Sinai Medical Center (US) | 2023-04-12 | — | — | EP | disclosed |
| WO-2022119842-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER (US) | 2022-06-09 | — | — | WO | disclosed |
| US-7388010-B2 | Quinoxalinone derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-06-17 | — | — | US | disclosed |
| US-7388010-B2 | Quinoxalinone derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-06-17 | — | — | US | disclosed |