Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.57 |
| ▸ | PSD | A5PKW4 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805900 | 0.91 | CNR1 (0.62) | CNR1CYP3A4CYP2C9CYP2C19AVPR2 | |
| SCHEMBL4807441 | 0.91 | CNR1 (0.70) | CNR1PSDCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14181067 | 0.91 | CNR1 (0.70) | CNR1PSDCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14181074 | 0.90 | CNR1 (0.68) | CNR1PSDCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14181126 | 0.86 | CNR1 (0.68) | CNR1PSDCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14181073 | 0.80 | CNR1 (0.81) | CNR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14180990 | 0.80 | CNR1 (0.81) | CNR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14181128 | 0.80 | CNR1 (0.70) | CNR1CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL14181050 | 0.80 | CNR1 (0.70) | CNR1CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL13114674 | 0.80 | CNR1 (0.50) | CNR1CYP3A4CYP2C9CYP2C19AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |