Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027321 | 1.00 | TACR1 (0.46) | TACR1CHRNB4CHRNA3KDM4ETDP1 | |
| SCHEMBL4361732 | 1.00 | TACR1 (0.46) | TACR1CHRNB4CHRNA3KDM4ETDP1 | |
| SCHEMBL14027339 | 0.84 | CHRNB4 (0.53) | TACR1CHRNB4CHRNA3KDM4EMEN1 | |
| SCHEMBL4160343 | 0.78 | TACR1 (0.42) | TACR1KDM4ETDP1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4906259 | 0.78 | TACR1 (0.41) | TACR1KDM4ETDP1MEN1ALDH1A1 | |
| SCHEMBL4909495 | 0.77 | TACR1 (0.40) | TACR1KDM4ETDP1MEN1ALDH1A1 | |
| SCHEMBL4370819 | 0.76 | SLC6A4 (0.41) | TACR1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL14027319 | 0.76 | SLC6A4 (0.41) | TACR1KDM4EMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL4909632 | 0.75 | SLC6A4 (0.40) | TACR1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL14027690 | 0.75 | KDM4E (0.51) | KDM4ETDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |