SCHEMBL14190064

SCHEMBL14190064

CC(C)(C)OC(=O)COCCCCCCNC(=N)NC(=O)c1nc(Cl)c(N)nc1N

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCNN1A P37088 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4418467 0.86 SCNN1A (0.41) SCNN1A
SCHEMBL4885148 0.86 SCNN1A (0.44) SCNN1A
SCHEMBL4884819 0.86 SCNN1A (0.44) SCNN1A
SCHEMBL4883729 0.86 SCNN1A (0.44) SCNN1A
SCHEMBL4415794 0.86 SCNN1A (0.44) SCNN1A
SCHEMBL4884842 0.86 SCNN1A (0.44) SCNN1A
SCHEMBL4412096 0.86 SCNN1A (0.44) SCNN1A
SCHEMBL14088104 0.85 SCNN1A (0.47) SCNN1A
SCHEMBL14088092 0.84 SCNN1A (0.44) SCNN1A
SCHEMBL14190103 0.84 SCNN1A (0.49) SCNN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7375107-B2 Such as N-(6-aminohexyl)-N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)guanidine Dihydrochloride; for hydration of mucosal surfaces, treating chronic bronchitis, cystic fibrosis, sinusitis, vaginal dryness, dry eye, esophogitis, emphysema, and pneumonia PARION SCIENCES, INC. (US) 2008-05-20 US disclosed