Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 13/20 | 0.74 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.74 |
| ▸ | TUBB | P07437 | 7/20 | 0.74 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.74 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.74 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.74 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.74 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.74 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.74 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.74 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.74 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.74 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.74 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.74 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.74 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030786 | 0.86 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12593827 | 0.86 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17145723 | 0.86 | TUBB1 (0.60) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2144727 | 0.85 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL291905 | 0.85 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL291904 | 0.85 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29611250 | 0.85 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29501731 | 0.85 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL91388 | 0.85 | TUBB1 (0.76) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13952732 | 0.84 | TUBB1 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384925-B2 | 2' Hydroxy-3'-bromo-3,4,4',5-tetramethoxy-(Z)-stilbene; antimitotic agent; inhibits the assembly of tubulin into microtubules; anticarcinogenic: solid tumor cancers, neovascularization; tubulin-binding stilbenoid analogs structurally related to combretastatin A-1 and A-4 (extract from willow tree) | OXIGENE, INC. (US) | 2008-06-10 | — | — | US | disclosed |