SCHEMBL14195095

SCHEMBL14195095

Cc1cc2c3c(cccc3c1O)C(=N)NC2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.39
▸ PARP1 P09874 4/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ USP2 O75604 2/20 0.39
▸ NPSR1 Q6W5P4 2/20 0.39
▸ RGS12 O14924 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ APEX1 P27695 1/20 0.39
▸ CASP1 P29466 1/20 0.39
▸ BRCA1 P38398 1/20 0.39
▸ MTOR P42345 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ CASP7 P55210 1/20 0.39
▸ GNAI1 P63096 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14195097 0.86 CDK2 (0.40) MAPTPARP1KMT2AMEN1USP2
SCHEMBL14278200 0.81 MAPT (0.37) MAPTPARP1KMT2AMEN1USP2
SCHEMBL27633139 0.70 KMT2A (0.63) MAPTPARP1KMT2AMEN1USP2
SCHEMBL9968963 0.70 MEN1 (0.62) MAPTPARP1KMT2AMEN1USP2
SCHEMBL21573605 0.69 HTT (0.40) MAPTPARP1KMT2AMEN1NPSR1
SCHEMBL28401578 0.68 PARP1 (0.47) MAPTPARP1KMT2AMEN1USP2
SCHEMBL10028837 0.68 PARP1 (0.73) MAPTPARP1KMT2AMEN1USP2
SCHEMBL14278202 0.67 CDK2 (0.39) MAPTPARP1KMT2AMEN1USP2
SCHEMBL27653625 0.66 KMT2A (0.46) MAPTPARP1KMT2AMEN1USP2
SCHEMBL25837793 0.65 KDM4E (0.42) MAPTKMT2ACYP1A2POLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358984-B2 Image forming apparatus including multibeam exposure unit having surface emitting laser array FUJI XEROX CO., LTD. (JP) 2008-04-15 — — US disclosed
US-7341810-B2 Electrophotographic photoreceptor method of manufacturing electrophotographic photoreceptor, and electrophotographic apparatus and process cartridge using electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2008-03-11 — — US disclosed
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