SCHEMBL14195271

SCHEMBL14195271

NCCCC[C@@H](C=O)NC(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 12/20 0.78
▸ NAALAD2 Q9Y3Q0 5/20 0.60
▸ RIMKLA Q8IXN7 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11986738 0.94 FOLH1 (0.78) FOLH1NAALAD2RIMKLA
SCHEMBL1741931 0.88 FOLH1 (1.00) FOLH1NAALAD2RIMKLA
SCHEMBL15739372 0.88 FOLH1 (1.00) FOLH1NAALAD2RIMKLA
SCHEMBL15739351 0.88 FOLH1 (1.00) FOLH1NAALAD2RIMKLA
SCHEMBL15739333 0.88 FOLH1 (1.00) FOLH1NAALAD2RIMKLA
SCHEMBL2450650 0.88 FOLH1 (1.00) FOLH1NAALAD2RIMKLA
SCHEMBL2450656 0.88 FOLH1 (1.00) FOLH1NAALAD2RIMKLA
SCHEMBL4669761 0.88 FOLH1 (1.00) FOLH1NAALAD2RIMKLA
SCHEMBL19352015 0.86 FOLH1 (0.97) FOLH1NAALAD2RIMKLA
SCHEMBL29331330 0.84 FOLH1 (0.62) FOLH1NAALAD2RIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3353152-B1 METHOD NORSK MEDISINSK SYKLOTRONSENTER AS (NO) 2021-09-15 — — EP disclosed
WO-2008058192-A2 HETERODIMERS OF GLUTAMIC ACID MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2008-05-15 — — WO disclosed
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