Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 20/20 | 0.93 |
| ▸ | S1PR1 | P21453 | 20/20 | 0.93 |
| ▸ | S1PR3 | Q99500 | 20/20 | 0.93 |
| ▸ | LPAR2 | Q9HBW0 | 20/20 | 0.93 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.67 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14195726 | 0.99 | S1PR2 (0.91) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL14195624 | 0.96 | S1PR2 (1.00) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL14195724 | 0.96 | S1PR2 (0.86) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL14195599 | 0.96 | S1PR2 (1.00) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL14195597 | 0.96 | S1PR2 (1.00) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL14195602 | 0.96 | S1PR2 (1.00) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL14195739 | 0.89 | S1PR2 (0.74) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL14195737 | 0.89 | S1PR2 (0.74) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL14195736 | 0.88 | S1PR2 (0.72) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL14195732 | 0.87 | S1PR2 (0.74) | S1PR2S1PR1S1PR3LPAR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351725-B2 | N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists | MERCK & CO., INC. (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351725-B2 | N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists | MERCK & CO., INC. (US) | 2008-04-01 | — | — | US | disclosed |