Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | CDK1 | P06493 | 1/20 | 0.62 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 18/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13938480 | 0.94 | KIT (0.62) | KITAURKACDK1MAP2K6PDGFRB | |
| SCHEMBL13962610 | 0.93 | KIT (0.61) | KITAURKACDK1MAP2K6PDGFRB | |
| SCHEMBL13938479 | 0.93 | KIT (0.63) | KITAURKACDK1MAP2K6PDGFRB | |
| SCHEMBL13938485 | 0.91 | KIT (0.69) | KITAURKACDK1MAP2K6PDGFRB | |
| SCHEMBL13938483 | 0.91 | KIT (0.68) | KITAURKACDK1MAP2K6PDGFRB | |
| SCHEMBL13938477 | 0.90 | KIT (0.60) | KITAURKACDK1MAP2K6PDGFRB | |
| SCHEMBL13938469 | 0.90 | KIT (0.67) | KITAURKACDK1MAP2K6PDGFRB | |
| SCHEMBL13938482 | 0.88 | KIT (0.63) | KITAURKACDK1MAP2K6PDGFRB | |
| SCHEMBL14196199 | 0.88 | KIT (0.68) | KITAURKACDK1MAP2K6PDGFRB | |
| SCHEMBL13938466 | 0.88 | KIT (0.68) | KITAURKACDK1MAP2K6PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055233-A1 | PROTEIN KINASE INHIBITORS | SUPERGEN, INC. (US) | 2008-05-08 | — | — | WO | disclosed |