Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 19/20 | 0.70 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | KIT | P10721 | 5/20 | 0.53 |
| ▸ | SRC | P12931 | 5/20 | 0.53 |
| ▸ | FLT3 | P36888 | 5/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.53 |
| ▸ | INSR | P06213 | 2/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572850 | 0.91 | CSF1R (0.68) | CSF1RSYKKITSRCFLT3 | |
| SCHEMBL14196352 | 0.91 | CSF1R (0.83) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL14196128 | 0.90 | CSF1R (0.73) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL4573781 | 0.90 | CSF1R (0.72) | CSF1RSYKKITSRCFLT3 | |
| SCHEMBL14196164 | 0.90 | CSF1R (0.72) | CSF1RSYKKITSRCFLT3 | |
| SCHEMBL4891395 | 0.89 | CSF1R (0.71) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL14196338 | 0.88 | CSF1R (0.73) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL14196162 | 0.86 | CSF1R (0.78) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL4573741 | 0.86 | CSF1R (0.85) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL4881838 | 0.83 | CSF1R (0.68) | CSF1RKITSRCFLT3NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055013-A2 | 5-OXO-5,8 - DIHYDRO - PYRIDO - PYRIMIDINES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-08 | — | — | WO | disclosed |