Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 19/20 | 0.65 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882029 | 1.00 | CYP11B1 (0.65) | CYP11B1CYP11B2ABCG2 | |
| SCHEMBL14197361 | 0.86 | CYP11B1 (0.67) | CYP11B1CYP11B2 | |
| SCHEMBL30634442 | 0.85 | CYP11B1 (0.76) | CYP11B1CYP11B2ABCG2 | |
| SCHEMBL17723918 | 0.85 | CYP11B1 (0.76) | CYP11B1CYP11B2ABCG2 | |
| SCHEMBL4883516 | 0.82 | CYP11B1 (0.62) | CYP11B1CYP11B2 | |
| SCHEMBL14197359 | 0.82 | CYP11B1 (0.62) | CYP11B1CYP11B2 | |
| SCHEMBL17723916 | 0.79 | CYP11B1 (1.00) | CYP11B1CYP11B2 | |
| SCHEMBL4882023 | 0.75 | ABCG2 (0.46) | CYP11B1ABCG2 | |
| SCHEMBL28269480 | 0.74 | CYP11B1 (0.51) | CYP11B1CYP11B2 | |
| SCHEMBL30634452 | 0.72 | CYP11B1 (1.00) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799649-B1 | 3-(2-HYDROXYPHENYL) PYRAZOLES AND THEIR USE AS HSP90 MODULATORS | MERCK PATENT GMBH (DE) | 2014-06-25 | — | — | EP | disclosed |
| US-20080090880-A1 | 3-(2-Hydroxyphenyl) Pyrazoles and Thier Use as Hsp90 Modulators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-04-17 | — | — | US | disclosed |
| US-20080090880-A1 | 3-(2-Hydroxyphenyl) Pyrazoles and Thier Use as Hsp90 Modulators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090880-A1 | 3-(2-Hydroxyphenyl) Pyrazoles and Thier Use as Hsp90 Modulators | HSP90AB1, HSP90AA1, HSP90AB2P | CYP11B1 630/4885CYP11B2 733/4885ABCG2 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.