SCHEMBL14199550

SCHEMBL14199550

CCCCS(=O)(=O)Nc1ccccc1C(=O)Cl

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 1/20 0.50
KCNK3 O14649 1/20 0.49
KCNK9 Q9NPC2 1/20 0.49
PGAM1 P18669 1/20 0.48
MRGPRX1 Q96LB2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043836 0.94
SCHEMBL10646481 0.94
SCHEMBL27919527 0.91 KCNA5 (0.59) KCNA5KCNK3
SCHEMBL13743071 0.87
SCHEMBL10434954 0.85 KCNA5 (0.50) KCNA5KCNK3KCNK9PGAM1MRGPRX1
SCHEMBL25219425 0.84 CYP1A2 (0.56) KCNA5KCNK3KCNK9MRGPRX1
SCHEMBL11667006 0.84
SCHEMBL8609056 0.82
SCHEMBL12201484 0.82 MRGPRX1 (0.50) MRGPRX1
SCHEMBL12200974 0.82 MRGPRX1 (0.50) MRGPRX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080081926-A1 SULFONYLAMINOBENZOIC ACID AND SALT SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-04-03 US disclosed
US-20080081926-A1 SULFONYLAMINOBENZOIC ACID AND SALT SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081926-A1 SULFONYLAMINOBENZOIC ACID AND SALT SLC5A1, SLC5A2, SLC1A5 KCNA5 119/4885KCNK3 842/4885KCNK9 774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.