Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200226 | 0.90 | KDM4E (0.60) | KDM4ECYP2D6CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL20347952 | 0.86 | KDM4E (0.55) | KDM4EPOLBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL10254237 | 0.86 | KDM4E (0.59) | KDM4ECYP2D6POLBL3MBTL1TSHR | |
| SCHEMBL10223621 | 0.85 | KDM4E (0.78) | KDM4EPOLBL3MBTL1TSHRALDH1A1 | |
| SCHEMBL14228228 | 0.85 | CYP2D6 (0.50) | KDM4ECYP2D6CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL179256 | 0.82 | CYP1A2 (0.76) | KDM4ECYP2D6CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL13763492 | 0.82 | KDM4E (0.53) | KDM4ECYP2D6CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL12781675 | 0.80 | CYP2D6 (0.57) | KDM4ECYP2D6CYP1A2CYP3A4L3MBTL1 | |
| SCHEMBL4404318 | 0.79 | KDM4E (0.75) | KDM4ECYP1A2POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10183563 | 0.79 | CYP1A2 (0.63) | KDM4ECYP2D6CYP1A2CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778874-B2 | Glycopeptide antibiotic monomer derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | KDM4E 4340/4885CYP2D6 427/4885CYP1A2 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.