Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200183 | 0.90 | CA1 (0.39) | — | |
| SCHEMBL14229345 | 0.88 | TP53 (0.36) | TP53 | |
| SCHEMBL14200186 | 0.86 | CA1 (0.34) | ESR2 | |
| SCHEMBL14229451 | 0.84 | CA1 (0.43) | TP53 | |
| SCHEMBL14200390 | 0.84 | TP53 (0.32) | TP53 | |
| SCHEMBL14200218 | 0.81 | CNR2 (0.39) | ESR2TP53 | |
| SCHEMBL14200202 | 0.81 | CNR2 (0.33) | ESR2 | |
| SCHEMBL14200435 | 0.81 | — | — | |
| SCHEMBL14200221 | 0.80 | CES1 (0.33) | ESR2 | |
| SCHEMBL14200209 | 0.80 | CES1 (0.33) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |