Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.83 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408549 | 0.94 | CNR2 (0.83) | CNR2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4410691 | 0.91 | CNR2 (1.00) | CNR2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4551332 | 0.91 | CNR2 (0.89) | CNR2ALDH1A1TP53LMNA | |
| Hydrochloric Acid SCHEMBL8077978 | 0.90 | CNR2 (0.98) | CNR2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4414684 | 0.89 | CNR2 (0.78) | CNR2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL4407867 | 0.89 | CNR2 (0.78) | CNR2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL4418658 | 0.87 | CNR2 (0.75) | CNR2 | |
| SCHEMBL4416446 | 0.85 | CNR2 (0.73) | CNR2MEN1KMT2ATSHRHTT | |
| SCHEMBL4405983 | 0.85 | CNR2 (1.00) | CNR2 | |
| SCHEMBL4409929 | 0.85 | CNR2 (1.00) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358245-B2 | Treatment of gastroesophageal reflux disease | ASTRAZENCA AB (SE) | 2008-04-15 | — | — | US | disclosed |